Chloral hydrate와 Hydroxyzine의 경구투여와 N₂O-O₂병용투여시 진정효과에 관한 연구
A STUDY ON THE CONSCIOUS SEDATIVE EFFECT OF CHLORAL HYDRATE/HYDROXYZINE WITH AND WITHOUT N₂O-O₂
홍성준, 이긍호,
소속 상세정보
홍성준 ( ) - 경희대학교 치과대학 소아치과학교실
이긍호 ( ) - 경희대학교 치과대학 소아치과학교실
KMID : 0358920020290040489
Abstract
경희대학교 치과대학병원 소아차과에 내원한 환자 중, negative이거나 definitively negative로 분류되는, 전신적으로 건강한(ASA Ⅰ) 4세미만의 아동 20명(평균 30.8개월, 남아 12명 , 여아 8명)을 대상으로 하여, 두 차례의 진료를 시행하였다. 첫 진료시 chloral hydrate(50kg/kg)와 hydroxyzine HCI(25mg)만을 경구투여하고, 동일한 대상에게 두 번째 진료시
chloral hydrate (50mg/kg)와 hydroxyzine HCI(25mg)의 경구투여와 함께 N₂O-O₂를 병용하여 통상의 보존적 처치를 시행하였다. 각 치료과정 별로 나타나는 진정효과를 Houpt의 평가표(수면, 울음, 움직임, 전반적 행동지수)에 의해 측정하였고, pulse oximeter를 이용하여 맥박수 및 동맥혈 산소포화도의 차이 등을 비교, 평가하여 그 결과 chloral hydrate와 hydroxyzine HCl의 경구투여와 함께 N₂O-O₂를 병용한 경우가 chloral hydrate와 hydroxyzine만을 경구투여한 경우에 비해 어린이의 행동조절에 더 바람직한 진정요법인 것으로 판단된다.
The purpose of this study was to compare the clinical sedation effect of chloral hydrate and hydroxyzine combination with and without nitrous oxide/oxygen inhalation when young children were sedated for dental treatment. The uncooperative 20 children aged, 21 to 47 months of age(ASA Class I ), participated in the study. The author examined 20 children(male 12, female 8). Each patient was assigned to receive chloral hydrate(50mg/kg) and hydroxyzine(25mg). Next appointment, each patient was assigned to receive N20´-02, choral hydrate and hydroxyzine.
Sleep, crying, movement, and overall behavior response were evaluated, and the sedative effects were evaluated by Houpt´s rating scale. Pulse rate and peripheral oxygen saturation were also measured for monitoring the sedated patients during treatment period by pulse oximeter..
The result were as follows :
1. In the evaluation of sleep scores, crying scores, and movement scores, chloral hydrate/hydroxyzine/N20-02 combination group was significantly rated high (p<0.05).
2. In the evaluation of overall behavior scores, chloral hydrate/hydroxyzine/N20-02 combination group was significantly rated high(p(0.05).
3. In the evaluation of overall behavior evaluation scores(by Houpt), 93.3% in chloral hydrate/hydroxyzine/ N20-02 combination group and 63.3% in chloral hydrate/hydroxyzine combination group were rated "good" or "very good".
4. There was no adverse side effect(i.e. respiratory depression) in both group.
키워드
chloral hydrate;hydroxyzine;N₂O-O₂;경구 투여;Chloral hydrate;Hydroxyzine;N₂O-O₂;Oral administration
원문 및 링크아웃 정보
등재저널 정보